Chemistry : Aromatic Nitro to Amine reduction
Applicable : When the nitro and amine are both soluble in water
‘Greener’ alternative to conventional approach :
- The nitro is reduced in the presence of Newreka’s proprietary catalysts “G-Cat” and “R-Cat”
- The spent G-Cat is filtered out and the rest is sent to a crystallizer and centrifuge from where the amine is taken out
- The mother liquor is treated with R-Cat to remove organic and inorganic impurities and then recycled into the process
Advantages :
| Economics | – | Increase profitability by over 5% through a Profit-Centric approach |
| Quality | – | High Purity, low Impurity profile while integrating Recycle@SourceTM Solutions |
| Quantity | – | High selectivity leading to increase in yield by 5-10% |
| Productivity | – | Reduce process batch time by 30% |
| Environment | – | Minimize liquid effluents by 80% |
| Safety | – | Freedom from high pressure, incidental hazards, pyrophoricity, acidic and alkaline conditions |
| Energy | – | Minimize energy consumption by 20% |
Products that can benefit from this technology :
| Nitro | CAS no | Amine | CAS no |
| 4-nitrophenol | 100-02-7 | 4-aminophenol | 123-30-8 |
| 2-nitrophenol | 88-75-5 | 2-aminophenol | 95-55-6 |
| 2-chloro-3-nitro-4- methyl pyridine | 23056-39-5 | 2-chloro-3-amino-4- methyl pyridine | 133627-45-9 |
| 4-nitroso meta cresol | 615-01-0 | 4-amino meta cresol | 2835-99-6 |
| 1,3-dimethyl-5-nitroso uracil |
6632-68-4 | Theophiline | 58-08-2 |
Successfully Industrialized :
- In over 5 API & API Intermediate manufacturing companies having E-Factor of more than 50 (E-Factor = Kg Waste /Kg Product)
- 10+ Fine Chemicals Industry (Agro, Dyes, Pigments & its intermediate manufacturers)- with E-Factor of more than 25
Case-study :
More than 800 successful Recycle loops set up for an API Intermediate. click here to read customer feedback.
Industrial Green Chemistry World 